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Review Article

Stasis Dermatitis: A Review of Differential Diagnosis, Pathogenesis, and Current Treatment Options
March 20, 2025 PDT
Stasis Dermatitis: A Review of Differential Diagnosis, Pathogenesis, and Current Treatment Options
Hadar Lev-TovGary S FriedmanItai OphirBonnie VlahosGang WangRobert Norman

Stasis dermatitis is characterized by troublesome symptoms that significantly impact quality of life. This review discusses the diagnosis, treatment, management and associated complications of stasis dermatitis.

Patient Reported Outcome Measures in Complementary & Alternative Medicine for Atopic Dermatitis: A Systematic Review
March 18, 2025 PDT
Patient Reported Outcome Measures in Complementary & Alternative Medicine for Atopic Dermatitis: A Systematic Review
Jiwon ParkPeter Lio

Patient-reported outcomes collect vital information about the impact treatments have on quality of life. This article reviews patient-reported outcomes from trials of complementary and alternative therapies for atopic dermatitis.

Topical Integrative Treatments for Pruritus: A Comprehensive Review
March 07, 2025 PDT
Topical Integrative Treatments for Pruritus: A Comprehensive Review
Aileen ParkLeo WanPeter Lio

Botanical oils, herbal extracts, vitamin oils, honey, vinegar, and baking soda. This review examines the evidence for these topical therapies for pruritus, providing insights for integrating them into treatments.

A Review on the Incorporation of Sodium Lauryl Sulfate into Homemade Cleansers to Avoid Fragrances and Preservatives
March 03, 2025 PDT
A Review on the Incorporation of Sodium Lauryl Sulfate into Homemade Cleansers to Avoid Fragrances and Preservatives
Shailey C. ShahKatlyn M. SmahaRobin C. YiMatthew J. ZirwasSteven R. Feldman

Explore the properties that sodium laurel sulfate brings to soaps and cleansers. This article provides a framework for counseling patients in incorporating this ingredient when making homemade soap.

February 25, 2025 PDT
Idiopathic cutaneous dysesthesia and the importance of multidisciplinary management
Megan HauptmanJeffrey SobierajJohn KooMio Nakamura

Idiopathic cutaneous dysesthesia (ICD) presents as abnormal skin sensations without clear causes, often linked to nervous system dysfunction. This review explores its pathophysiology, diagnosis, psychiatric comorbidities, and multidisciplinary management strategies.

January 27, 2025 PDT
From Discovery to Modern Understanding: The Acid Mantle in Dermatology
Isabella J. TanPeter A. Lio

The acid mantle plays a significant role in the skin barrier, pH balance, and microbiome. Understanding its function has advanced holistic skincare and therapeutic potential in dermatology.

Neuronal Changes in Atopic Dermatitis: Insights into Neuroimmunological Changes in AD and Therapeutic Implications
January 27, 2025 PDT
Neuronal Changes in Atopic Dermatitis: Insights into Neuroimmunological Changes in AD and Therapeutic Implications
Peter LioMary McCarthy

This review of the neuronal pathways involved in eczema highlights their role in mitigating itch, while also exploring the role of the nervous system in the pathophysiology of disease.

Epithelial Barrier Hypothesis: A Systematic Review
December 24, 2024 PDT
Epithelial Barrier Hypothesis: A Systematic Review
Krishna PatelPeter Lio

The epithelial barrier hypothesis explains that damage to the epithelia by external agents can result in dysbiosis, inflammation, and allergy.

External Factors and the Cutaneous Microbiome
October 08, 2024 PDT
External Factors and the Cutaneous Microbiome
Shin Young (Grace) YuPeter Lio

This review highlights the external factors that influence the skin microbiome, including outdoor and indoor environmental factors, social dynamics, lifestyle, and personal care products.

Exploring the Impact of Psychotherapeutic Interventions on Inflammatory Skin Conditions
September 13, 2024 PDT
Exploring the Impact of Psychotherapeutic Interventions on Inflammatory Skin Conditions
Annika M HansenPeter Lio

This review explores the bidirectional relationship between the skin and the mind, highlighting the role of psychotherapeutic interventions in diseases such as eczema, psoriasis, and acne vulgaris.

September 03, 2024 PDT
Inositol for Treating Dermatological Disorders: A Systematic Review
Myiah QuachYu-Feng ChangIrene (Tai-Lin) LeeFranchesca ChoiApple Bodemer

Inositol is widely used to treat metabolic conditions, hormonal regulation, and neurodegenerative diseases. This review highlights that inositol may be a safe and effective adjunctive therapy for acne and hirsutism.

August 29, 2024 PDT
Baking Soda and the Skin: A Review of Baking Soda in Dermatology
Carline DuguéMaya BaiyasiShanelle JacksonStarling TolliverSteven Daveluy

Findings from this review suggest that baking soda may be an effective and safe dermatologic agent in various capacities.